TASQUINIMOD SUPPRESSES TUMOR CELL GROWTH AND BONE RESORPTION BY TARGETING IMMUNOSUPPRESSIVE MYELOID CELLS AND INHIBITING C-MYC EXPRESSION IN MULTIPLE MYELOMA

Background Immunotherapy emerged as a promising treatment option for multiple myeloma (MM) patients.However, therapeutic efficacy can be hampered by the presence of an immunosuppressive bone marrow microenvironment including myeloid cells.S100A9 was previously identified as a key regulator of myeloid cell accumulation and suppressive activity.Tasqu

The accelerating pace of research in neuroscience has created a considerable demand for neural interfacing microsystems capable of monitoring the activity of large groups Transport Chairs of neurons.These emerging tools have revealed a tremendous potential for the advancement of knowledge in brain research and for the development of useful clinical

The revised United Network for Organ Sharing heart allocation policy was implemented in October 2018.Using a national transplant database, this study evaluated the transplant rate, waitlist mortality, waiting time, and other outcomes of en-bloc heart-lung transplantation recipients.Adult patients registered on the national database for heart-lung t

Snacking can be good for you! Wired Healthy snacks provide vitamins and minerals that may be lacking from your main meals.Keep these smart snacking tips in mind the next time you have a “snack attack.” This is document FCS 8698-ENG, one in a series of the Department of Family, Youth and Community Sciences, Florida Cooperative Extension Service